BioNourish Moisturizing Vaginal Gel: The Benefits of Hyaluronic Acid

BioNourish™Moisturizing Vaginal Gel with Hyaluronic Acid mimics natural female secretions and provides sustained moisturizing relief. Certain medical conditions may compromise vaginal tissue, making it difficult for it to retain its own moisture.

Lock in moisture with Hyaluronic Acid; this luxurious, water-based formula provides immediate and long-term hydration for the most sensitive tissue in the body. Patent-pending formula designed to mimic optimal pH and salt levels, BioNourish Moisturizing Vaginal Gel with Hyaluronic Acid supports lasting moisture.

Additional Features:

  • Bio-Matched® to the body’s own natural lubrication
  • Isotonic* formula to rebalance optimal vaginal pH and naturally occurring salts
  • Paraben and glycol-free
  • Does not contain hormones; widely used to address vaginal dryness during and post-oncology

*denoting or relating to a solution having the same osmotic pressure as some other solution, especially one in a cell or a body fluid.


BioNourish provides relief of vaginal dryness by improving hydration of vaginal tissues.

Why it matters:

  • Hyaluronic acid topical approach with a liquid preparation for vaginal use to control signs and symptoms of vulvovaginal atrophy (VVA) in postmenopausal women demonstrated significant effectiveness both in terms of objective and subjective improvement in vaginal dryness and dyspareunia.
    Eur Rev Med Pharmacol Sci. 2016; 20(20):4190–4195 1
  • Both hyaluronic acid vaginal gel and estriol cream are effective in the treatment of vaginal dryness in menopausal women, but superior relief was found with hyaluronic acid in symptoms of urinary incontinence, cellular maturation and vaginal dryness.
    The Journal of Sexual Medicine, Volume 10, Issue 6 (2013): 1575-1584 2
    International Journal of Community-Based Nursing and Midwifery; vol. 4,1 (2016): 69-78. 4

Hyaluronic acid may improve tissue consistency.

Why it matters:

  • Hyaluronic acid, this compound has been largely studied and investigated in many dermatologic, ocular and osteoarticular applications requiring tissue remodeling; vaginal atrophy has also been investigated with promising results. The results of the present investigation with a hyaluronic acid-based vaginal liquid strongly supports the indication of such a preparation for the relief of genital symptoms due to vulvo-vaginal atrophy (VVA.) In terms of mechanisms of action details, the high molecular weight hyaluronic acid acts as a protective macromolecule for the vaginal mucosa, and also favors penetration of the low molecular weight molecules into the deeper vaginal layers.
    European Review for Medical and Pharmacological Sciences; 2016; 20: 4190-4195 
  • Hyaluronic Acid is a natural polysaccharide that forms an important part of the extra-cellular  matrix  of  the  skin  and  This substance is able to conserve a large amount of water molecules and, due to the properties like formation and conservation of extra-cellular inflation, skin moistening in the case of inflammation and preservation of water equilibrium has a key role. Also, it is very effective in treatment of skin diseases by preserving tissue consistency, facilitating cellular emigration in cases of inflammation, and improving and regenerating of the tissues.
    International Journal of Community-Based Nursing and Midwifery; vol. 4,1 (2016): 69-78.   4


  1. Origoni M, Cimmino C, Carminati G, Iachini E, Stefani C, Girardelli S, et al. Postmenopausal vulvovaginal atrophy (VVA) is positively improved by topical hyaluronic acid application: a prospective, observational study. Eur Rev Med Pharmacol Sci. 2016;20(20):4190–4195.
  2. Chen, Junya et. al. Evaluation of the Efficacy and Safety of Hyaluronic Acid Vaginal Gel to Ease Vaginal Dryness: A Multicenter, Randomized, Controlled, Open‐Label, Parallel‐Group, Clinical Trial
    The Journal of Sexual Medicine, Volume 10, Issue 6 (2013): 1575-1584.
  3. Postmenopausal vulvovaginal atrophy (VVA) is positively improved by topical hyaluronic acid application. A prospective, observational study M. ORIGONI et al; European Review for Medical and Pharmacological Sciences; 2016; 20: 4190-4195
  4. Jokar, Azam et al. “Comparison of the Hyaluronic Acid Vaginal Cream and Conjugated Estrogen Used in Treatment of Vaginal Atrophy of Menopause Women: A Randomized Controlled Clinical Trial.” International journal of community based nursing and midwifery vol. 4,1 (2016): 69-78.,cannot%20take%20local%20hormone%20treatment.

Additional References

  • Bukhari SNA, Roswandi NL, Waqas M, Habib H, Hussain F, Khan S, et al. Hyaluronic acid, a promising skin rejuvenating biomedicine: a review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects. Int J Biol Macromol. 2018;120(Pt B):1682–95.
  • Poetschke, H. Schwaiger, S. Steckmeier, T. Ruzicka, G.G. Gauglitz, Anti-wrinkle creams with hyaluronic acid: how effective are they?, MMW Fortschr. Med. 158 (Suppl. 4) (2016 May 25) 1–6.
  •  Narurkar VA, Fabi SG, Bucay VW, et al. A New Approach in Topical Hyaluronic Acid; Going Beyond Instant Benefits to Restore Epidermal HA Homeostasis. J Drug Dermatol. 2016:15(1 Suppl2);s24-s37.
  • Manjula Jegasothy, Valentina Zabolotniaia, Stephan Bielfeldt, Efficacy of a new topical nano-hyaluronic acid in humans, J. Clin. Aesthet. Dermatol. 7 (3) (2014 Mar) 27–29.

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